In-vivo live imaging ,   ȳͼ ϰ 輼??
reagent ̿ϴĿ ޶ ֽϴ.
, ɺ ص帳ϴ.
In vivo Live Image ֻ Nano-probe!

 


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   Neo-Live  Endocytosis ɷ labeling DZ    

   media ˸ 󵵷 ֱ⸸ ϸ ˴ϴ. ׷

   ϰų ɸ ʽϴ.

 

   ̼?

   Neo-Lives Endocytosis ؼ uptake Ǵ Դϴ.

   , ʽϴ.

 

 

       One-Step Procedure

 

   

 

 

 

 

 

 

   ÿ 䳢 ƺ

  Neo Live  magnetic core ÿ ֽϴ.

  ׷ ϳ reagent ̹ MRI

   ֽϴ.

 

   ð ״!

  Neo Live Silica shell ܴ ׿ֽϴ.

 ׷  Ÿǰ ð ӵ˴ϴ.

 

 

Particle

 

 

 

 

   迡 ° ص帳ϴ.

  Neo Live ǥ鿡 پ biomolecules ó ֽϴ.

  ׷ Ͻô ǰ ôٸ, 迡 ° ֹ 帳ϴ.

 


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1. Photostability  (in vitro data)

 

 

 

4. High Sensitivity in small cell number (in vivo live image)

Fig.1.

Neo-STEM A549 cell 30а UV Ǿ

(Red: Neo-STEM, Blue: DAPI)

Fig.2.

a) Neo-STEM hMSC 7 Ŀ Ȯ

b) Neo-STEM bone marrow stem cell osteoblast ȭϸ鼭

ϴ Ȯ

 

 

Fig.3.

a) Positive control b) Neo-STEM conjugation G-STP antibody IHC

 

 

3. Conjugation with various biomolecules

   - Targeting, bioimaging, cell sorting, drug delivery

 

 

 

2. Long term Cell Tacking

Fig.4.

a) Neo-Live cell (5X103, 2.5X103)

b) (7.5 X 104)

 

 

5. Deep tissue imaging (in vivo live image)

 

Fig.5.

a) Neo-Live cell brain

b) Neo-Live cell spinal cord

 

 

 

6. Long term in vivo Cell Tacking (in vivo live image)

Fig.6.

Neo-Live chondrocyte cell articular capsule injury mouse

30 Ŀ Ȯ

 

 

 

 

7. MRI (in vivo live image)

 

Fig.7. A549 cell Neo-STEM (TMSR) mouse subcutaneous injection MRI Ȯ Live Image

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


ǰ ֹ


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