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70¿©°³ÀÇ Protein Áß¿¡¼­

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°¢Á¾ inhibitor, agonist, antagonist - Screening - Quantitation

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Screening tool, ÀÌ·± ºÐµé²² ÃßõÇØ µå¸³´Ï´Ù

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- Pathway »çÀÌ¿¡ ¾î¶² crosstalkÀÌ Á¸ÀçÇÏ´ÂÁö ¾Ë°íÀÚ ÇϽô ºÐ


½±°í °£ÆíÇÑ ½ÇÇè ¹æ¹ýÀ» ¿øÇϽŴٸé... Proteome Profiler Antibody Array kit


- MembraneÀ» ÀÌ¿ëÇÑ screening tool

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Human Adipokine array kit (Cat# ARY024, 58 analytes)

Adiponectin Angiopoietin-1 Angiopoietin-2 Angiopoietin-like 2 Angiopoietin-like 3 BAFF/BLyS
BMP-4 Cathepsin D Cathepsin L Cathepsin S CCL2/MCP-1 CCL5/RANTES
Chemerin Complement Factor D C-Reactive Protein CXCL8/IL-8 DPPIV/CD26 Endocan
EN-RAGE Fetuin B FGF basic FGF-19 Fibrinogen Growth Hormone
HGF ICAM-I IGFBP-2 IGFBP-3 IGFBP-4 IGFBP-6
IGFBP-rp1/IGFBP-7 IL-1 beta IL-6 IL-10 IL-11 LAP (TGF-ß1)
Leptin LIF Lipocalin-2/NGAL M-CSF MIF Myeloperoxidase
Nidogen-1/Entactin Oncostatin M Pappalysin-1/PAPP-A PBEF/Visfatin PCSK9 Pentraxin-3
Pref-1/DLK-1/FA1 RAGE Resistin Serpin A12 Serpin A8/AGT Serpin E1/PAI-1
TIMP-1 TIMP-3 TNF-alpha VEGF

Human Adipokine array kit insert È®ÀÎÇϱâ

Mouse Adipokine array kit (Cat# ARY013, 38 analytes)

Adiponectin AgRP ANGPT-L3 CCL2/MCP-1/JE CCL5/RANTES CRP
DPPIV/CD26 Endocan Fetuin A FGF acidic FGF-21 HGF
ICAM-1 IGF-I IGF-II IGFBP-1 IGFBP-2 IGFBP-3
IGFBP-5 IGFBP-6 IL-6 IL-10 IL-11 Leptin
LIF Lipocalin-2/NGAL  M-CSF OSM PAI-1/Serpin E1 PTX2
PTX3 Pref-1 RAGE RBP4 Resistin TIMP-1
TNF-alpha VEGF

Mouse Adipokine array kit insert È®ÀÎÇϱâ

Rat Adipokine array kit (Cat# ARY016, 30 analytes)

ANGPT-L3 CCL2/MCP-1/JE CCL5/RANTES DPPIV/CD26 Endocan FGF-21
HGF ICAM-1 IGF-I IGF-II IGFBP-1 IGFBP-2
IGFBP-3 IGFBP-5 IGFBP-6 IL-1 beta IL-6 IL-10
IL-11 Leptin LIF Lipocalin-2/NGAL M-CSF PAI-1/Serpin E1
Pref-1 RAGE Resistin TIMP-1 TNF-alpha VEGF 

Rat Adipokine array kit insert È®ÀÎÇϱâ

ÆĶõ»ö: Quantikine ELISA kitÀ¸·Î Á¤·® , »¡°£»ö: DuoSet ELISA kitÀ¸·Î Á¤·®, º¸¶ó»ö: Quantikine, DuoSet µÑ ´Ù °¡´É


Screening°ú Á¤·®À» µ¿½Ã¿¡! Luminex assay


 

- Sample 50 ¥ìL·Î ÃÖ´ë 100°¡Áö ´Ü¹éÁú µ¿½Ã Á¤·®

- R&D Quantikine ELISA (ELISA Gold Standard)¿Í ÃÖ°íÀÇ correlation

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Human Obesity Panel

Adiponectin, CRP, MCP-1, Complement Factor D, IL-6, IL-10, Leptin, Resistin, Serpin E1, TNF-¥á


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  • ºñ¸¸ / ´ç´¢¿Í °ü·ÃµÈ TOCRIS small molecules (Inhibitor, Activator, Peptide)

Cat#

Product

Ghrelin Receptor

3374

Cortistatin 14 - Endogenous neuropeptide; binds sst1 - sst5 and ghrelin receptor

3033

Cortistatin-8 - Ghrelin receptor antagonist

1463

Ghrelin (human) - Endogenous ghrelin receptor agonist

1465

Ghrelin (rat) - Endogenous ghrelin receptor agonist

2951

[Des-octanoyl]-Ghrelin (rat) - Major circulating form of ghrelin; devoid of activity at GHS receptor

1346

des-Gln14-Ghrelin (rat) - Endogenous ghrelin receptor ligand

2260

[Des-octanoyl]-Ghrelin(human)

- Major circulating form of ghrelin; devoid of activity at ghrelin receptor but is active in vivo

1922

[D-Lys3]-GHRP-6 - Ghrelin receptor antagonist

2261

L-692,585 - Potent, non-peptide ghrelin receptor agonist

1946

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
- Potent ghrelin receptor full inverse agonist. Also antagonist at other neuropeptide receptors. Anticancer in vitro 
Leptin

2985

LEP (116-130) (mouse) Synthetic leptin peptide fragment
Insulin and Insulin-like Receptors
Inhibitors

4774

BMS 536924 - Dual IR/IGF1R inhibitor 

5111

GSK 1838705 - Potent and selective IR and IGF1R inhibitor; antitumor 

2956

Picropodophyllotoxin - Selective IGF1R inhibitor 

2768

PQ 401 - IGF1R inhibitor 
Activators

1819

Demethylasterriquinone B1 - Selective insulin RTK activator 

3435

Insulin (human) recombinant expressed in yeast - Endogenous peptide agonist 
Ligand Sets

5154

HNGF6A - Humanin analog; increases insulin sensitivity 

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Lipid metabolism & Obesity

Peptides Involved in Appetite Modulation

Insulin Signaling

Adipocytokines & Insulin Signaling Pathway

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