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R&D assay for Alzheimer's Disease

 

Alzheimer's Disease´Â ±â¾ï°ú ¾ð¾î¸¦ °üÀåÇÏ´Â neurocortex, hippocampus¿¡¼­ ½Å°æ ¼¼Æ÷ÀÇ ºñ ÀÌ»óÀûÀÎ Á×À½¿¡ ÀÇÇØ ³ªÅ¸³ª°Ô µÇ´Â Áúº´ÀÔ´Ï´Ù. 1906³â¿¡ óÀ½ º´¸íÀÌ È®¸³µÆÀ¸³ª Áö±Ý±îÁöµµ Alzheimer's DiseaseÀÇ ¿øÀÎÀÌ ¸íÈ®ÇÏ°Ô ¹àÇôÁöÁö ¾Ê¾Ò½À´Ï´Ù.

¿õºñ¸ÞµðÅØ¿¡¼­´Â Alzheimer's Disease ¿¬±¸¿¡¼­ °¡Àå ¸¹ÀÌ »ç¿ëµÇ´Â ´Ù¾çÇÑ Á¾·ùÀÇ Amyloid ¥â peptides, Neuroinflammation, ½Å°æ¼¼Æ÷ÀÇ apoptosis pathway, °¢Á¾ proteaseÀÇ ¹ßÇöÀ» ÇѲ¨¹ø¿¡ È®ÀÎÇÒ ¼ö ÀÖ´Â Antibody array, Alzheimer's Disease ¿¬±¸¿¡ ÇÊ¿äÇÑ ³ôÀº qualityÀÇ ´Ù¾çÇÑ antibody µî Alzheimer's Disease ¿¬±¸¿¡ ÇÊ¿äÇÑ ´Ù¾çÇÑ Á¦Ç°µéÀ» Á¦°øÇÏ°í ÀÖ½À´Ï´Ù.


1. Proteome Profiler Antibody Array kit


- Cell signal, pathway °ü·Ã markers¸¦ ÇÑ ÀåÀÇ membrane¿¡¼­ È®ÀÎ!

 - ¼Ò·®ÀÇ sample·Î 100¿©°³ ´Ü¹éÁú µ¿½Ã ºÐ¼®

 - Antibody array ÀÌ¿ë ³í¹® Áß 91%ÀÇ ³í¹®ÀÌ  R&D Proteome Profiler¸¦ ¼±ÅÃ

 - Western blotº¸´Ù ½±°í ºü¸¥ ½ÇÇè¹æ¹ý!

 

ÀÌ·± ºÐµé²² ÃßõÇØ µå¸³´Ï´Ù!

- ƯÁ¤ ¾à¹° ó¸® ÈÄ neuroinflammationÀÇ Â÷À̸¦ º¸°íÀÚ ÇϽô ºÐ

   Human XL Cytokine array kit (Cat# ARY022, 102 analytes)

   >>> IL-1~31, IFN-gamma, TNF-alpha, FGF-basic µî ÃÑ 102°³ÀÇ ¿°Áõ °ü·Ã cytokineµé È®ÀÎ °¡´É

 

- Neuron cell apoptosis pathway¿¡ ¾î¶² º¯È­°¡ ÀÖ´ÂÁö È®ÀÎÇÏ°íÀÚ ÇϽô ºÐ

   Human Cell stress array kit (Cat# ARY018, 26 analytes)

   >>> Bcl-2, COX-2, HIF-1/-2alpha, NF-kappaB2, pp53, HSP70 µî ÃÑ 26°³ cell stress marker È®ÀÎ °¡´É

 

- Alzheimer's Disease¿Í °ü·ÃµÈ °¢Á¾ protease, protease inhibitor markerµéÀÇ ¹ßÇöÀ» ÇÑ ´«¿¡ º¸°íÀÚ ÇϽô ºÐ

   Human Protease (34 analytes) / Protease Inhibitor (32 analytes) array kit (Cat# ARY025)

   (Protease marker 2Àå, Protease Inhibitor 2Àå)

   Human Protease array kit (Cat# ARY021, 34 analytes)

   Human Protease Inhibitor array kit (Cat#ARY023, 34 analytes)

   >>> ADAM ½Ã¸®Áî, MMP½Ã¸®Áî, Cathepsin ½Ã¸®Áî, Kallikrein ½Ã¸®Áî µî ÃÑ 34°³ protease marker È®ÀÎ °¡´É

   >>> APP, EMMPRIN, Sertpin ½Ã¸®Áî, TIMP-1~4 µî ÃÑ 35°³ protease inhibitor È®ÀÎ °¡´É


2. Amyloid-¥â peptide, ¥ã-scretase inhibitor, Amyloid-¥â inhibitor


- TOCRIS¸¸ÀÇ unique product ´Ù¼ö º¸À¯

- ´Ù¾çÇÑ ¿¬±¸ ºÐ¾ß¿¡ ´ëÇÑ »õ·Ó°í Æø ³ÐÀº Á¦Ç° Á¦°ø

- ion channel molecules, signaling inhibitor, agonist, antagonist

- Cell biology, cancer, neuroscience, signal transduction, stem cell, epigenetics

 

- ´Ù¾çÇÑ Á¾·ùÀÇ amyloid ¥â peptide ¹× amyloid ¥â inhibitor

- Amyloid ¥â¿Í ƯÀÌÀûÀ¸·Î ¹ÝÀÀÇÏ´Â Çü±¤ dye

- ´Ù¾çÇÑ Á¾·ùÀÇ ¥ã-secretase inhibitor

º¸´Ù ¸¹Àº Alzheimer's disease¿Í °ü·ÃµÈ inhibitor, chemical list¸¦ È®ÀÎÇϽ÷Á¸é Ŭ¸¯ÇØÁÖ¼¼¿ä!


3. IHC, Western blot¿ë antibodyµé


- Full-sequence antigenÀ¸·Î Á¦ÀÛµÈ high-sensitivity antibody

- ±ØÇÑ »óȲ¿¡¼­µµ activity¸¦ º¸ÀÌ´Â ¿ì¼öÇÑ Ç°ÁúÀÇ antibody

- È­Çк¸Á¸Á¦ ´ë½Å  ½ÇÇè¿¡ ¿µÇâÀ» ¹ÌÄ¡Áö ¾Ê´Â Trehalose¸¦ ÀÌ¿ëÇÑ antibody

¾ËÃ÷ÇÏÀÌ¸Ó È¯ÀÚÀÇ ³ú¿¡¼­ È®ÀÎÇÑ phospho-APP

(»ç¿ëÁ¦Ç°: cat# MAB2508)

¾ËÃ÷ÇÏÀÌ¸Ó È¯ÀÚÀÇ ³ú¿¡¼­ È®ÀÎÇÑ RAGE

(»ç¿ëÁ¦Ç°: cat# AF1145)

»ç¶÷ÀÇ ³ú¿¡¼­ È®ÀÎÇÑ Presenilin-1

(»ç¿ëÁ¦Ç°: cat# AF149)

»ç¶÷ÀÇ ³ú¿¡¼­ È®ÀÎÇÑ Cathepsin B

(»ç¿ëÁ¦Ç°: cat# AF953)

Alzheimer's disease¿Í °ü·ÃµÈ °¢Á¾ antibody, protein list È®ÀÎÀº ºê·Î¼Å¸¦ Âü°íÇØÁÖ¼¼¿ä!


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Neurodegeneration

Product guide

R&D assays for

Alzheimer's Disease

APP metabolism

& A¥â plaque formation

 

 

 

Neuroinflammation

Blood-Brain Barrier (BBB)

SNARE and

synaptic adhesion molecule

ÀüÈ­ ¶Ç´Â ¸ÞÀÏ·Î ¿¬¶ô Áֽøé ÇÊ¿äÇÑ ÀÚ·á Àü´ÞÇØ µå¸®µµ·Ï ÇÏ°Ú½À´Ï´Ù

 

Á¦Ç°»ó´ã: Çмú¸¶ÄÉÆÃÆÀ ÇѼҿµ (techserv@woongbee.com / 031-776-3300 ³»¼± 122)