2016.07.18

 

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R&D Systems, a Bio-Techne brand Novus Biologicals, a Bio-Techne brand Tocris, a Bio-Techne brand Protein Simple, a Bio-Techne Brand

 

neuroscience enews

Bio-Techne Newsletter | July 14, 2016

 

 

 

2016 7¿ù Bio-Techne Neuroscience Newsletters

 

Huntington's disease (HD)

- Tocris new poster

- Boston Biochem E3 ligase enzymes


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Huntington's Disease (HD) Poster from Tocris

 

Huntington's Disease (HD) Poster from Tocris
HD modeling iPSCs¿¡¼­  HD pathology °ü·Ã ¼¼Æ÷ ³» signaling pathway¿¡ ´ëÇÏ¿© ¿¬±¸ÇÑ Æ÷½ºÅ͸¦ Tocris¿¡¼­ È®ÀÎÇÏ½Ç ¼ö ÀÖ½À´Ï´Ù. (ÀúÀÚ: Annalena Wieland and Nicholas Allen, University of Cardiff)

 

 

The Best E3 Ligase Enzymes for HD Research
E3 ligases´Â µ¹¿¬º¯ÀÌ Huntingtin (mHtt) ´Ü¹éÁúÀ» ºÐÇØÇÏ´Â È¿¼ÒÀ̸ç, E3 ligasesÀÇ ±â´ÉÀå¾Ö´Â HD¿¡ ±â¿©ÇÒ ¼ö ÀÖ½À´Ï´Ù. Ubiquitin-related Á¦Ç°ÀÇ ¼±µÎÁÖÀÚÀÎ Bio-Techne's Boston Biochem¿¡¼­ E3 ligases¸¦ ´Ù¾çÇÏ°Ô ¸¸³ªº¸½Ç ¼ö ÀÖ½À´Ï´Ù!

 

 

Mouse Monoclonal Antibody for mHtt (Clone 1A771)
Huntingtin (mHtt)¿¡ ÀÇÇØ ¾ß±â µÈ Ubiquitin-positive neuronal intranuclear inclusions (NIIs)´Â Huntington's Áúº´¿¡¼­ ½Å°æ Àå¾Ö ¹× º¯¼º¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÕ´Ï´Ù. Novus Biologicals
ÀÇ anti-Huntingtin monoclonal antibody (clone 1A771) ´Â mHtt ´Ü¹éÁúÀ» ¼±ÅÃÀûÀ¸·Î È®ÀÎÇÒ ¼ö ÀÖ½À´Ï´Ù.

 

 

A 769662-Induced AMPK Activation Reduces mHtt Aggregates
HD pathologyÀÇ Å« Ư¡Àº mHTTÀÇ ÃàÀûÀÔ´Ï´Ù. ÃÖ±Ù ¿¬±¸¿¡ µû¸£¸é HD mouse model¿¡¼­ À¯·¡ÇÑ STHdh cell¿¡¼­ A 769662¿¡ ÀÇÇØ À¯µµ µÈ MAPKÀÇ È°¼ºÀº mTOR-independent autophagy¸¦ À¯µµÇϸç, ±× °á°ú·Î
mHTTÀÇ ÃàÀûÀ» °¨¼Ò ½ÃŲ´Ù°í ÇÕ´Ï´Ù. (ÀúÀÚ: Walteret al.)

 

A New Pathogenic Factor in Parkinson's Disease

 

Luminex® Assays for Human Neuroscience Biomarkers R&D Systems´Â ½Å°æÅðÇ༺ Áúȯ °ü·Ã biomarkersÀÎ GFAP, Park5/UCH-L1, Park7/DJ-1, Tau, and Synuclein-¥áÀ» Human Luminex assay Á¦Ç°À¸·Î ÃÖ±Ù »õ·Î Ãâ½Ã ÇÏ¿´½À´Ï´Ù.

 

Bio-Techne Travel Grants Available to ASCB 2016

 

Bio-Techne Travel Grants Available to ASCB 2016
R&D systems°¡ 2016³â 12¿ù 3ÀÏ-7ÀÏ °³ÃÖÇÏ´Â ASCB Âü¼®ÀÚ¸¦ À§ÇØ $1000 ¿©Çà °æºñ¸¦ Áö¿øÇØ µå¸³´Ï´Ù. Áö±Ý ½ÅûÇϼ¼¿ä! Apply Now!

 

Bio-Techne at Upcoming Meetings

Cambridge Stem Cell Institute 5th International Symposium 2016
Cambridge, UNITED KINGDOM, July 18-19

Summer Frontiers 2016 - Systems Biology of Innate Immunity 2016
Nijmegen, NETHERLANDS, September 7-9

Association Nationale des Enseignants de Biologie Cellulaire 2016
Paris, FRANCE, September 22-24

 

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