Neuroscience Research Area

Bio-Techne Newsletter | January 23, 2018

 

 

 

2018 1¿ù Bio-Techne Neuroscience Newsletter

 

-        Huntington's disease ¿¬±¸¸¦ À§ÇÑ ÀÚ·á ¹× Á¦Ç°

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Huntington's Disease Poster from Tocris

 

Huntington's Disease Poster from Tocris
University of Cardiff
ÀÇ Annalena Wieland °ú Nicholas Allen¿¡ ÀÇÇØ ¾²¿©Áø ÀÌ Æ÷½ºÅÍ´Â Huntington's disease ÀÇ º´¸®Çп¡ ±âÀÎÇÑ medium spiny neuron intracellular signaling pathways¸¦ ¿ä¾àÇÑ °ÍÀÔ´Ï´Ù. Request ¶Ç´Â download ÇÏ½Ç ¼ö ÀÖ½À´Ï´Ù!

 

Huntingtin Aggregates Sequester Key Autophagy Targets

 

Huntingtin Aggregates Sequester Key Autophagy Targets
Huntington's disease
¿¡¼­, È®À强 polyglutamine tracts ¸¦ °¡Áø Huntingtin (Htt)ÀÇ µ¹¿¬º¯ÀÌÇüÀº autophagy proteinµéÀÎ  mTOR¿Í Beclin1À» »óÈ£ÀÛ¿ë½ÃÅ°°í ºÐ¸®ÇÏ´Â ¼¼Æ÷ ³» ÀÀÁýü¸¦ Çü¼ºÇÑ´Ù. Neurodegeneation³» autophagy ¸¦ ¿¬±¸ÇÏ½Å´Ù¸é ¿ì¸®ÀÇ ÀÚ·áµéÀ» °Ë»öÇغ¸¼¼¿ä!

 

New R&D Systems ELISA for GIT1

 

New R&D Systems® ELISA for GIT1
Spine morphology ¿Í neural plasticity¸¦ Á¶ÀýÇÏ´Â GTPase-activating proteinÀÎ GIT1Àº Htt ÀÀÁý¼ºÀ» Çâ»ó½ÃÅ°°í Huntington's disease º´¸®¸¦ ÃËÁø½ÃÅ°´Â °ÍÀ¸·Î ³ªÅ¸³µ½À´Ï´Ù. R&D Systems´Â ½Ã·á¿¡¼­ GIT1ÀÇ ¼öÁØÀ» ÃøÁ¤ÇÒ ¼ö ÀÖ´Â DuoSet® ELISA Development kit¸¦ Á¦°øÇÏ°í ÀÖ½À´Ï´Ù.

 

Investigate Nrf2 with Tocris Small Molecules

 

Investigate Nrf2 with Tocris Small Molecules
»õ·Î¿î paper ¿¡¼­, ¼¼Æ÷¼Õ»ó¿¡ ´ëÇÑ protection¿¡ °ü¿©ÇÏ´Â À¯ÀüÀÚ Á¶Àý¿¡ À־ transcription factor Nrf2ÀÇ ¿ªÇÒ¿¡ ´ëÇØ ÀÚ¼¼È÷ ±â¼úÇÏ°í ÀÖ½À´Ï´Ù. Nrf2ÀÇ ±â´ÉÀº Huntington's diseaseÀ» ºñ·ÔÇÑ ¸¹Àº ½Å°æ ÅðÇ༺ Áúȯ¿¡¼­ º¯ÇüµÇ¾î ÀÖ½À´Ï´Ù. Tocris small molecules À» È°¿ëÇÑ Nrf2 ¸¦ ¿¬±¸ÇØ º¸¼¼¿ä.

 

MiMPCs: A Therapeutic Option for Nerve Regeneration?

 

MiMPCs: A Therapeutic Option for Nerve Regeneration?
»õ·Ó°Ô Ãâ°£µÈ ³í¹®ÀÇ ÀúÀÚ´Â À¯µµµÈ mesenchymal progenitor cells (MiMPCs)°¡ Schwann cells¿Í µ¿ÀÏÇÑ neurotrophic factors¸¦ ºÐºñÇÑ´Ù´Â »ç½ÇÀ» º¸¿©ÁÖ±â À§ÇØ R&D Systems® ELISAs¸¦ È°¿ëÇÏ¿© ÀÌµé ¼¼Æ÷°¡ ½Å°æ ¼ºÀå°ú Àç»ýÀ» Áö¿øÇÏ´Â µ¥ »ç¿ëµÉ ¼ö ÀÖÀ½À» Á¦½ÃÇß½À´Ï´Ù.

 

The Industry's Gold-Standard ELISAs for Measuring Neurotrophic Factors

 

The Industry's Gold-Standard ELISAs for Measuring Neurotrophic Factors
¸¹Àº neurotrophic factorsÀÇ º¯ÇüµÈ ¼öÄ¡´Â ´Ù¾çÇÑ Á¤½Åº´ ¹× ½Å°æ ÅðÇ༺ Áúº´°ú °ü·ÃµÇ¾î ¿Ô½À´Ï´Ù. R&D Systems® Quantikine® ELISAs¸¦ »ç¿ëÇÏ¿© ½Ã·áÀÇ neurotrophic levels¸¦ ÃøÁ¤ÇØ º¸¼¼¿ä.

 

Wall Poster: Periodic Table of Neurotrophic and Neurotactic Factors

 

Wall Poster: Periodic Table of Neurotrophic and Neurotactic Factors
Neurotrophic ¹× neurotactic factors¿¡ ´ëÇØ ´õ ¾Ë°í ½ÍÀ¸¼¼¿ä? ¿ì¸®ÀÇ wall poster´Â °¢±â ´Ù¸¥ families ±×¸®°í ±×°ÍµéÀÇ ¸â¹öµé, °¢ ¿ä¼Ò¿¡ °áÇÕÇÏ´Â receptors ¶Ç´Â ligandsµîÀ» °³°ýÇÏ°í ÀÖ½À´Ï´Ù. Áö±Ý Request ÇØ º¸¼¼¿ä!

 

Bio-Techne at Upcoming Meetings

2018 Midwinter Conference of Immunologists
Asilomar, USA, January 27-30, 2018

MedLab 2018
Dubai, UAE, February 5-8, 2018

13th Biomarker Congress 2018
Manchester, UNITED KINGDOM, February 15-16, 2018

FENS 2018
Berlin, GERMANY, July 7-11, 2018

 

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