Immunology eNewsletter

 

Immunology Newsletter

l  Cell Therapy ¿¬±¸¿¡ ÃÖÀûÈ­ µÈ GMP Protein!

l  ½ÅÁ¦Ç°! Mouse Apoptosis Antibody Array Kit

l  Biosimilar Antibody & Anti-Idiotype Antibody

 

 

 

 

GMP Proteins

 

GMP Proteins for Therapeutic Manufacturing

 

R&D Systems® ¿¡¼­ GMP cytokines°ú growth factor¸¦ Ãâ½ÃÇß½À´Ï´Ù. ÀÌ Á¦Ç°µéÀº cell therapy ¿¬±¸¿¡ »ç¿ëÇÒ ¼ö ÀÖµµ·Ï USP Chapter <1043>, USP Chapter <92>¿¡ µû¶ó ¸¸µé¾îÁ³½À´Ï´Ù.

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Mouse Apoptosis Array

 

New Proteome Profiler¢â Mouse Apoptosis Array

 

Mouse Apoptosis Antibody Array Kit°¡ Ãâ½ÃµÆ½À´Ï´Ù!

ÇϳªÀÇ Cell lysate¿¡¼­ 21°³ÀÇ apoptosis marker¸¦ È®ÀÎÇÒ ¼ö ÀÖ½À´Ï´Ù.

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Anti-Idiotype Antibodies

 

R&D Systems Now Offers Biosimilar and Anti-Idiotype Antibodies

 

ÃÖ±Ùantibody drug °³¹ßÀÌ È°¹ßÈ÷ ÁøÇàµÊ¿¡ µû¶ó, R&D Systems¿¡¼­ antibody drug ¿¬±¸¿¡ »ç¿ëÇÒ ¼ö ÀÖ´Â antibodyµéÀ» Ãâ½ÃÇß½À´Ï´Ù. Biosimilar ¸¦ targetÀ¸·Î ÇÏ´Â Á¦Ç°µé°ú Anti-Idiotype antibody Á¦Ç° list¸¦ È®ÀÎÇغ¸¼¼¿ä.

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Immune checkpoint

 

Immune Checkpoint Inhibitors from Tocris

 

Immune checkpoint moleculesÀº immunosuppressive signaling pathway¿Í °ü·ÃµÈ immune cell receptor¸¦ inhibitionÇÕ´Ï´Ù. Tocris´Â (D)-PPA 1,¸¦ ºñ·ÔÇÏ¿© PD-L1/PD-1 interaction blocker, tumor growth inhibitor µî ´Ù¾çÇÑ small moleculeµéÀ» Ãâ½ÃÇÏ°í ÀÖ½À´Ï´Ù.

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Biotinylated Proteins

 

New Biotinylated Proteins: Specificity Backed by Activity Data

 

R&D Systems¿¡¼­ immuno-oncology °ü·Ã biotinylated cytokineµéÀ» Ãâ½ÃÇß½À´Ï´Ù. Biotinylated IL-2, IL-6, VISTA, VSIG4, PD-L2¿Ü ´Ù¾çÇÑ Á¦Ç°µéÀÇ activity data¸¦ È®ÀÎÇØ º¸¼¼¿ä.

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Immuno-Oncology Research

 

Explore Our Collection of Products for Immuno-Oncology Research

 

»õ·Î¿î immune checkpoint regulatorµéÀÌ ¾Ë·ÁÁö¸é¼­ cancer immunotherapyÀÇ »õ·Î¿î targetÀÌ µÇÁö ¾ÊÀ»±î ÇÏ´Â ±â´ë°¨ÀÌ ³ô¾ÆÁö°í ÀÖ½À´Ï´Ù. ¾î¶²regulatorµéÀÌ ÀÖ´ÂÁö, ¿¬±¸¿¡ »ç¿ëÇÒ ¼ö ÀÖ´Â Á¦Ç°µéÀº ¾î¶² °ÍµéÀÌ ÀÖ´ÂÁö, R&D systems¿¡¼­ ¹ß°£ÇÑ Immuno-Oncology Brochure¸¦ ÅëÇؼ­ È®ÀÎÇغ¸¼¼¿ä.
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Targeting MDSCs

 

Targeting MDSCs for Cancer Immunotherapy

 

Myeloid-derived suppressor cells (MDSCs)Àº immunosuppressive Ư¡À» °¡Áö±â ¶§¹®¿¡ cancer Ä¡·á¿¡ À־ Å« Àå¾Ö¹°·Î ¿©°ÜÁý´Ï´Ù. R&D systems blog ¿¡¼­ MDSCs¸¦ targetÀ¸·Î ÇÏ´Â ÃֽŠ¿¬±¸ µ¿Çâ µîÀ» »ìÆ캸¼¼¿ä.

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MAPK Signaling Pathways

 

New Poster: Refresh Your MAPK Signaling Expertise

 

MAPK signaling dysfunctionÀº carcinogenesis¿Í ¿¬°ü ÀÖ½À´Ï´Ù. ÃÖ±Ù MAPK signaling inhibition°ú tumor immune response°¡ cancer immunotherapy ¿¬±¸ÀÚµé »çÀÌ¿¡¼­ Å« È­Á¦°¡ µÇ°í ÀÖ½À´Ï´Ù. MAPK signaling poster¸¦ ÅëÇØ key marker¸¦ È®ÀÎÇØ º¸¼¼¿ä.

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IL-10 Cytokines

 

New! IL-10 Cytokine Family Signaling Pathways

 

IL-10Àº pro-tumorigenic°ú anti-tumorigenic È¿°ú¸¦ º¸ÀÌ´Â cytokineÀ¸·Î Àß ¾Ë·ÁÁ® ÀÖ½À´Ï´Ù. IL-10 signaling pathway¸¦ ÅëÇØ IL-10 cytokine°ú °ü·ÃµÈ family cytokineµéÀÌ ¾î¶² »óÈ£ÀÛ¿ëÀ» ÇÏ´ÂÁö È®ÀÎÇØ º¸¼¼¿ä.

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Single Cell isolation Smart Aliquotor Single-Cell Isolation Easy to operate with high efficiency Exellent integrity for  PCR and sequencing Single-Cell Cloning High viability and high efficiency Easy to track whole cloning process Rare Cell Isolation From gene edited cells(i.e CRISPR) From clinical samples (i.e.blood) Single-Cell PCR sigle-cell isolation and identification in situ lysis of identified single cell transfer of lysate into PCR tube cDNA synthesis and amplification Operation is very simple Only a common pipette is needed  for use and takes about 15 seconds Excellent cell compatibility It is compatible with isolation of cells that have diameters less than 5¥ìm. High yield and viability One Smart Aliquotor yields about  30 single cells, Which have high viability. Identifiable and selectable Each single can be easily identified and then selected. Features Operation by common pipettes Cell size ¡Â 50¥ìm idiameter Cloning in-situ clonal generation Single-cell yield ~30 cells per device Identification 1 well per second Time in aliquoting ~15 seconds Required cell numbers ¡Ã2cells Minimum aliquot volume 50nL Comparison of Single-Cell Isolation Methods Capability/Specifics Serial Dilution Micro- manipulation Flow Cytometry SMART ALIQUOTOR Simplicity and time consumption Controllability in transfer volume Compatibility in rare cell isolation Compatibility in cell size & shape Throughput Cell viability Cell selectivity Affordability