Immunology eNewsletter

 

Immunology Newsletter

l  Cell Therapy 연구에 최적화 GMP Protein!

l  신제품! Mouse Apoptosis Antibody Array Kit

l  Biosimilar Antibody & Anti-Idiotype Antibody

 

 

 

 

GMP Proteins

 

GMP Proteins for Therapeutic Manufacturing

 

R&D Systems® 에서 GMP cytokines growth factor 출시했습니다. 제품들은 cell therapy 연구에 사용할 있도록 USP Chapter <1043>, USP Chapter <92> 따라 만들어졌습니다.

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Mouse Apoptosis Array

 

New Proteome Profiler Mouse Apoptosis Array

 

Mouse Apoptosis Antibody Array Kit 출시됐습니다!

하나의 Cell lysate에서 21개의 apoptosis marker 확인할 있습니다.

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Anti-Idiotype Antibodies

 

R&D Systems Now Offers Biosimilar and Anti-Idiotype Antibodies

 

최근antibody drug 개발이 활발히 진행됨에 따라, R&D Systems에서 antibody drug 연구에 사용할 있는 antibody들을 출시했습니다. Biosimilar target으로 하는 제품들과 Anti-Idiotype antibody 제품 list 확인해보세요.

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Immune checkpoint

 

Immune Checkpoint Inhibitors from Tocris

 

Immune checkpoint molecules immunosuppressive signaling pathway 관련된 immune cell receptor inhibition합니다. Tocris (D)-PPA 1, 비롯하여 PD-L1/PD-1 interaction blocker, tumor growth inhibitor 다양한 small molecule들을 출시하고 있습니다.

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Biotinylated Proteins

 

New Biotinylated Proteins: Specificity Backed by Activity Data

 

R&D Systems에서 immuno-oncology 관련 biotinylated cytokine들을 출시했습니다. Biotinylated IL-2, IL-6, VISTA, VSIG4, PD-L2 다양한 제품들의 activity data 확인해 보세요.

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Immuno-Oncology Research

 

Explore Our Collection of Products for Immuno-Oncology Research

 

새로운 immune checkpoint regulator들이 알려지면서 cancer immunotherapy 새로운 target 되지 않을까 하는 기대감이 높아지고 있습니다. 어떤regulator들이 있는지, 연구에 사용할 있는 제품들은 어떤 것들이 있는지, R&D systems에서 발간한 Immuno-Oncology Brochure 통해서 확인해보세요.
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Targeting MDSCs

 

Targeting MDSCs for Cancer Immunotherapy

 

Myeloid-derived suppressor cells (MDSCs) immunosuppressive 특징을 가지기 때문에 cancer 치료에 있어서 장애물로 여겨집니다. R&D systems blog 에서 MDSCs target으로 하는 최신 연구 동향 등을 살펴보세요.

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MAPK Signaling Pathways

 

New Poster: Refresh Your MAPK Signaling Expertise

 

MAPK signaling dysfunction carcinogenesis 연관 있습니다. 최근 MAPK signaling inhibition tumor immune response cancer immunotherapy 연구자들 사이에서 화제가 되고 있습니다. MAPK signaling poster 통해 key marker 확인해 보세요.

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IL-10 Cytokines

 

New! IL-10 Cytokine Family Signaling Pathways

 

IL-10 pro-tumorigenic anti-tumorigenic 효과를 보이는 cytokine으로 알려져 있습니다. IL-10 signaling pathway 통해 IL-10 cytokine 관련된 family cytokine들이 어떤 상호작용을 하는지 확인해 보세요.

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-2018년 08월 27일-

Single Cell isolation Smart Aliquotor Single-Cell Isolation Easy to operate with high efficiency Exellent integrity for  PCR and sequencing Single-Cell Cloning High viability and high efficiency Easy to track whole cloning process Rare Cell Isolation From gene edited cells(i.e CRISPR) From clinical samples (i.e.blood) Single-Cell PCR sigle-cell isolation and identification in situ lysis of identified single cell transfer of lysate into PCR tube cDNA synthesis and amplification Operation is very simple Only a common pipette is needed  for use and takes about 15 seconds Excellent cell compatibility It is compatible with isolation of cells that have diameters less than 5μm. High yield and viability One Smart Aliquotor yields about  30 single cells, Which have high viability. Identifiable and selectable Each single can be easily identified and then selected. Features Operation by common pipettes Cell size ≤ 50μm idiameter Cloning in-situ clonal generation Single-cell yield ~30 cells per device Identification 1 well per second Time in aliquoting ~15 seconds Required cell numbers ≥2cells Minimum aliquot volume 50nL Comparison of Single-Cell Isolation Methods Capability/Specifics Serial Dilution Micro- manipulation Flow Cytometry SMART ALIQUOTOR Simplicity and time consumption Controllability in transfer volume Compatibility in rare cell isolation Compatibility in cell size & shape Throughput Cell viability Cell selectivity Affordability