Product List

B7-1/CD80 B7-2/CD86 B7-H2/ICOS L B7-H3 B7-H4
B7-H5/VISTA/PD-1H B7-H6 B7-H7/HHLA2 BTLA CD28
CTLA-4 HVEM/TNFRSF14 ICOS LIGHT/TNFSF14 Lymphotoxin-alpha/TNF-beta
PD-1 PD-L1 PD-L2 TMIGD2/CD28H  

 

Target

References

B7-H3

B7-H3 promotes colorectal cancer angiogenesis through activating the NF-B pathway to induce VEGFA expression

B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2

PD-1

PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells

PDL-2

Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells

 

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