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Stem Cell ¹× Organoids culture¸¦ À§ÇÑ Matrix !

R&D Systems ¿¡¼­´Â BME (Basement Membrane Extract)°¡ ÁغñµÇ¾î ÀÖ½À´Ï´Ù. ±â Matrigel »ç¿ëÀÚ¶ó¸é µ¿ÀÏ °³¹ßÀÚ, µ¿ÀÏ component ·Î ±¸¼ºµÈ Á¦Ç°À̹ǷΠ°ÆÁ¤ ¾øÀÌ »ç¿ë °¡´ÉÇϽʴϴÙ.

¸¸¾à ±âÁ¸ Á¦Ç°°úÀÇ ´ëüǰÀÌ ±Ã±ÝÇϽôٸé ÀúÈñ¿õºñ¸ÞµðÅØÀ¸·Î ¿¬¶ôÁÖ¼¼¿ä~

 

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Organoid Culture Protocols .

Organoid¸¦ ÁغñÁßÀ̽Ű¡¿ä? ConsistentÇÑ reagent·Î ÀçÇö¼º ÀÖ´Â Organoid¸¦ ¼¼ÆÃÇÒ ¼ö ÀÖ´Â R&D systemsÀÇ Organoid & 3D Cell Culture ProtocolÀ» È®ÀÎÇغ¸¼¼¿ä.

1. Human Liver Organoid Culture Protocol
2. Human Lung Organoid Culture Protocol

3. Human Gastric Organoid Culture Protocol

4. Production of
R-Spondin 1-conditioned media
5. Harvesting Organoid

6. Immunofluorescence of Organoids Embedded in Cultrex BME

7. Use of Cultrex BME to Improve Take and Growth of Xenografts in Mice

 

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GHP Healthcare & Pharmaceutical Awards – Most Innovative 3D Hydrogel System 2020

Drug discovery, Cell therapy, and personalized medicine ºÐ¾ß´Â Çõ½ÅÀûÀÎ ¿ª·®°ú ÀÛ¾÷ÀÌ ÇÊ¿äÇÑ ºÐ¾ßÀÔ´Ï´Ù. ÀÌ¿¡ ¸ÂÃç ´Ù¾çÇÑ Á¦Ç°°ú ½Å±â¼úµéÀÌ Ãâ½ÃµÇ´Â °¡¿îµ¥ Pharmaceutical Award 2020 ·Î½á Çõ½ÅÀûÀÎ Á¦Ç°ÀÌ ¸î ¸î ¼±Á¤ÀÌ µÇ¾ú½À´Ï´Ù.

Xeno-free, Injectable, Ready-to-Use, ½Ç¿Â ¾ÈÁ¤, Easy cell harvesting µî ¸¹Àº ÀåÁ¡À» °¡Áø VitroGel Hydrogel Matrix¸¦ ¼Ò°³ÇÕ´Ï´Ù.

 

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Small Intestinal Organoid from Human ESC and STAT3

Human ESC·ÎºÎÅÍ ¸¸µé¾îÁø small intestinal (SI) organoidÀÇ maturation¿¡ À־ STAT3ÀÇ ¿ªÇÒÀ» È®ÀÎÇÑ ³í¹®ÀÔ´Ï´Ù. SI organoid Á¦ÀÛ °úÁ¤°ú Á¦ÀÛµÈ organoid¸¦ È®ÀÎÇÏ´Â ¹æ¹ý µîÀ» ¾Ë¾Æº¼ ¼ö ÀÖ½À´Ï´Ù.

 

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Reference; Target organ-specific similarity of human iPSC-derived organoids and cells

Human iPSC¿¡¼­ À¯·¡µÈ organoid´Â ¾à¹° °³¹ß°ú Àç»ý ÀÇÇп¡ À¯¿ëÇÏ°Ô »ç¿ëµÇ´Âµ¥¿ä. ÀÌ·¸°Ô ¸¸µé¾îÁø organoid¿Í ½ÇÁ¦ Àå±â°¡ ¾ó¸¶³ª ¸¹Àº À¯»ç¼ºÀ» °¡Áö°í Àִ°¡¿¡ µû¶ó ¾à¹° °³¹ßÀÇ ¼ºÆа¡ Á¿ìµË´Ï´Ù. ÇØ´ç ³í¹®Àº Àå±â¿Í organoidÀÇ À¯»ç¼ºÀ» °´°üÀûÀ¸·Î È®ÀÎÇÒ ¼ö ÀÖ´Â ¹æ¹ýÀ» Á¦½ÃÇÕ´Ï´Ù

 

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Stem cellÀÇ Senescence ±âÀÛ È®ÀÎ

Normal cellsÀÇ DNA ¼Õ»óÀº ¹Ýº¹µÇ´Â cell division ¹× oxidative stress µî ´Ù¾çÇÑ ¿øÀÎÀ¸·Î ÀÎÇØ ¹ß»ýÇÏ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ½À´Ï´Ù. »Ó¸¸ ¾Æ´Ï¶ó ¾ÏÀ» Ä¡·áÇÏ·Á´Â ´Ù¾çÇÑ ½Ãµµ¿¡ ÀÇÇØ DNA ¼Õ»óÀ» ÀÏÀ¸Å°°í ¾Ï¼¼Æ÷»Ó¸¸ ¾Æ´Ï¶ó Á¤»óÀûÀÎ ¼¼Æ÷ÀÇ ³ëÈ­¸¦ ÃËÁøÇÕ´Ï´Ù.

ÃÖ±Ù ³ëÈ­°ü·ÃÁúȯ¿¡¼­ Àç»ý´É·ÂÀúÇÏÀÇ °³¼±À» À§ÇØ Stem cellÀÌ °¢±¤¹Þ°í ÀÖ½À´Ï´Ù. Senescence¿¬±¸¸¦ À§ÇÑ ´Ù¾çÇÑ ToolÀ» Dojindo Á¦Ç°À» ÅëÇØ È®ÀÎÇغ¸¼¼¿ä.

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R&D Systems Quantikine ELISA & Recombinant proteins for Stem Cell Research

ºÐÈ­ µÈ stem cellÀÇ function È®ÀÎÀº ELISAÀÇ Gold standardÀÎ R&D SystemsÀÇ Quantikine® ELISA Kit·Î ÁøÇàÇØ º¸½Ã±â ¹Ù¶ø´Ï´Ù.

Stem cell culture¿¡ ÇÊ¿äÇÑ recombinant proteinµµ È®ÀÎÇغ¸¼¼¿ä!

 

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3D&Organoids ¿¬±¸ ½Ã ´Ù¾çÇÏ°Ô È°¿ë µÉ ¼ö ÀÖ´Â Çü±¤ Probe ¹× DyeµéÀ» ¸¸³ªº¸¼¼¿ä.

ÃÖ±Ù Tocris¿¡¼­ ¾Æ·¡ »çÇ×À» Æ÷ÇÔÇÑ dye ¹× Probe Á¤º¸¸¦ ÇÑ °÷¿¡ ¸ð¾Æ ¾È³» µå¸®´Â ºê·Î¼Å¸¦ Ãâ½ÃÇß½À´Ï´Ù.

¢ºFluorescent Dyes
¢ºDyes for Flow Cytometry
¢ºFluorescent Probes
¢ºAnti-fade Reagents
¢ºBioluminescent Substrates
¢ºFluorogenic Dyes for Light-Up Aptamers
¢ºFluorescent Probes for Imaging Bacteria¢ºTSA Reagents for Enhancing IHC, ICC & FISH Signals

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Wide selection of BMEs and other ECMs for 3-D culturing Wide selection of BMEs and other ECMs for 3-D culturing

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